Hippolytus (c.185–c.235)

When the times are fulfilled, and the ten horns spring from the beast in the last (times), then Antichrist will appear among them. When he makes war against the saints, and persecutes them, then may we expect the manifestation of the Lord from heaven. (On Daniel, II, 7)

[I]n order that when those things [Antichrist’s mark of the beast] come to pass, we may be prepared for them, and not deceived. For when the times advance, he too, of whom these thing are said, will be manifested. (Treatise on Christ and Antichrist, 50)

Now, concerning the tribulation of the persecution which is to fall upon the Church from the adversary . . . . That refers to the one thousand two hundred and threescore days (the half of the week) during which the tyrant is to reign and persecute the Church. (Treatise on Christ and Antichrist, 60, 61)